Molecular Basis of Inheritance


  1. In the genetic code dictionary, how many codons are used to code for all the 20 essential amino acids?









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    Out of a total of 64 codons, 3 codons do not make any sense. Hence only 61 codons are used in the formation of the 20 essential amino acids (polypeptides).

    Correct Option: D

    Out of a total of 64 codons, 3 codons do not make any sense. Hence only 61 codons are used in the formation of the 20 essential amino acids (polypeptides).


  1. What would happen if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA?









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    UAA is the stop codon. Therefore at 25th amino acid the synthesis of polypeptide stops. So, a polypeptide of 24 Amino acid is formed.

    Correct Option: B

    UAA is the stop codon. Therefore at 25th amino acid the synthesis of polypeptide stops. So, a polypeptide of 24 Amino acid is formed.



  1. Which one of the following triplet codes, is correctly matched with its specificity for an amino acid in protein synthesis or as ‘start’ or ‘stop’codon?









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    AUG is initiating codon. UCG codes for serine, UUU codes for phenylalan, UGU codes for cysteine.

    Correct Option: A

    AUG is initiating codon. UCG codes for serine, UUU codes for phenylalan, UGU codes for cysteine.


  1. Which one of the following pairs of codons is correctly matched with their function or the signal for the particular amino acid?









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    GCU indicates alanine but GUU indicates valine. Stop codons are UAG, UGA and UAA AUG is the most common start codon which codes for methionine. UUA indicates leucine but UCA indicates serine.

    Correct Option: B

    GCU indicates alanine but GUU indicates valine. Stop codons are UAG, UGA and UAA AUG is the most common start codon which codes for methionine. UUA indicates leucine but UCA indicates serine.



  1. Molecular basis of organ differentiation depends on the modulation in transcription by









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    The process of formation of protein sequence from DNA strand is called transcription which requires RNA polymerase chain. RNA polymerase
    (i) RNA polymerase-I
    (ii) RNA polymerase II
    (iii) RNA polymerase-III

    Correct Option: D

    The process of formation of protein sequence from DNA strand is called transcription which requires RNA polymerase chain. RNA polymerase
    (i) RNA polymerase-I
    (ii) RNA polymerase II
    (iii) RNA polymerase-III