Molecular Basis of Inheritance
- Read the following four statements (A-D).
(A) In transcription, adenosine pairs with uracil.
(B) Regulation of lac operon by repressor is referred to as positive regulation.
(C) The human genome has approximately 50,000 genes.
(D) Haemophilia is a sex-linked recessive disease.
How many of the above statements are correct?
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Statement A & D is correct Regulation of lac operon by repressor is referred as negative regulation. In negative regulation, a repressor molecule binds to the operator of an operon and terminates transcription. In positive regulation, an activator interacts with the RNA polymerase in the promoter region to initiate transcription. Human genome contains some 20,000- 25,000 genes billion bases.
Correct Option: A
Statement A & D is correct Regulation of lac operon by repressor is referred as negative regulation. In negative regulation, a repressor molecule binds to the operator of an operon and terminates transcription. In positive regulation, an activator interacts with the RNA polymerase in the promoter region to initiate transcription. Human genome contains some 20,000- 25,000 genes billion bases.
- Given below is a sample of a portion of DNA strand. What is so special shown in it?
5’ —— GAATTC —— 3’
3’ —— CTTAAG —— 5’
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The sample of a portion of DNA strand shown in the figure is palindromic sequence of base pairs.
Correct Option: D
The sample of a portion of DNA strand shown in the figure is palindromic sequence of base pairs.
- The one aspect which is not a salient feature of genetic code, is its being:
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Genetic code is non ambiguous. There is no ambiguity for a particular codon. A particular codon will always code for the same amino acid, where ever it is found.
Correct Option: B
Genetic code is non ambiguous. There is no ambiguity for a particular codon. A particular codon will always code for the same amino acid, where ever it is found.
- What is not true for genetic code?
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The genetic code consists of 64 triplets of nucleotides. These triplets are called codons. With three exceptions, each codon encodes for one of the 20 amino acids used in the synthesis of proteins. That produces some redundancy in the code. Most of the amino acids being encoded by more than one codon. The genetic code can be expressed as either RNA codons or DNA codons.
Correct Option: D
The genetic code consists of 64 triplets of nucleotides. These triplets are called codons. With three exceptions, each codon encodes for one of the 20 amino acids used in the synthesis of proteins. That produces some redundancy in the code. Most of the amino acids being encoded by more than one codon. The genetic code can be expressed as either RNA codons or DNA codons.
- What would happen if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA?
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UAA is the stop codon. Therefore at 25th amino acid the synthesis of polypeptide stops. So, a polypeptide of 24 Amino acid is formed.
Correct Option: B
UAA is the stop codon. Therefore at 25th amino acid the synthesis of polypeptide stops. So, a polypeptide of 24 Amino acid is formed.