Molecular Basis of Inheritance


  1. Types of RNA polymerase required in nucleus for RNA synthesis?









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    Eukaryotes have three types of RNA polymerases:
    (i) RNA polymerase I - It is found in nucleus and is responsible for r-RNA synthesis.
    (ii) RNA polymerase II - It is found in nucleoplasm and is responsible for m-RNA synthesis.
    (iii) RNA polymerase III-It is found in nucleoplasm and is responsbile for t-RNA and 5-S RNA synthesis.

    Correct Option: C

    Eukaryotes have three types of RNA polymerases:
    (i) RNA polymerase I - It is found in nucleus and is responsible for r-RNA synthesis.
    (ii) RNA polymerase II - It is found in nucleoplasm and is responsible for m-RNA synthesis.
    (iii) RNA polymerase III-It is found in nucleoplasm and is responsbile for t-RNA and 5-S RNA synthesis.


  1. Exon part of m- RNAs have code for









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    Exons are the coding part of mRNA.

    Correct Option: A

    Exons are the coding part of mRNA.



  1. Out of 64 codons, 61 codons code for 20 types of amino acid. It is called









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    Out of 64 codons, only 3 signify stop codons. There are more than one codon for most of the amino acids, the genetic code is non-over lapping. Three successive nucleotides or bases code for only one amino acid wobbling refers to the third base degeneracy.

    Correct Option: A

    Out of 64 codons, only 3 signify stop codons. There are more than one codon for most of the amino acids, the genetic code is non-over lapping. Three successive nucleotides or bases code for only one amino acid wobbling refers to the third base degeneracy.


  1. Degeneration of a genetic code is attributed to the









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    According to the Wobble hypothesis, tRNA anticodon has the ability to wobble at its 5′end by pairing with even noncomplementary base of mRNA codon. It correspond to third base degeneracy of the codons.

    Correct Option: A

    According to the Wobble hypothesis, tRNA anticodon has the ability to wobble at its 5′end by pairing with even noncomplementary base of mRNA codon. It correspond to third base degeneracy of the codons.



  1. In the genetic code dictionary, how many codons are used to code for all the 20 essential amino acids?









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    Out of a total of 64 codons, 3 codons do not make any sense. Hence only 61 codons are used in the formation of the 20 essential amino acids (polypeptides).

    Correct Option: D

    Out of a total of 64 codons, 3 codons do not make any sense. Hence only 61 codons are used in the formation of the 20 essential amino acids (polypeptides).