Immunology Miscellaneous

Immunology Miscellaneous

Easy Questions
Moderate Questions
Difficult Questions

Immunology

Immunology Miscellaneous
  1. Three distinct antigens X, Y and Z were used to raise antibodies. Antigen Z was injected in a mouse on day zero followed by the administration of antigens X and Y on day 28. A second injection of antigen X was administered on day 70. The antibody titers were monitored in the serum every day and the results are shown below:

    Which one of the following statements regarding the antibody titers in the serum is INCORRECT ?








  1. View Hint View Answer Discuss in Forum

    Y- specific IgG will be high on day 84

    Correct Option: D

    Y- specific IgG will be high on day 84

  1. Production of monoclonal antibodies by hybridoma technology requires








  1. View Hint View Answer Discuss in Forum

    Splenocytes obtained from Spleen.

    Correct Option: A

    Splenocytes obtained from Spleen.

  1. Which one of the following complement proteins is the initiator of the membrane attack complex ?








  1. View Hint View Answer Discuss in Forum

    Main 4 complement proteins are the initiator of the membrane attack complex are (C5b, C6,C7 and C8).

    Correct Option: D

    Main 4 complement proteins are the initiator of the membrane attack complex are (C5b, C6,C7 and C8).

  1. Based on the heavy chain, which one of the following antibodies has multiple subtypes ?








  1. View Hint View Answer Discuss in Forum

    Only IgG and IgA has subtypes . IgG has 4 subtypes: Gamma1, Gamma2, Gamma3, Gamma4

    Correct Option: D

    Only IgG and IgA has subtypes . IgG has 4 subtypes: Gamma1, Gamma2, Gamma3, Gamma4

  1. Which of the following statement(s) is/are CORRECT for antigen activated effector T cells?
    P. CD4+ cells make contact with macrophages and stimulate their microbicidal activity
    Q. CD4+ cells make contact with B cells and stimulate them to differentiate into plasma cells
    R. CD8+ cells make contact with B cells and stimulate them to differentiate into plasma cells
    S. CD8+ cells make contact with virus infected cells and kill them








  1. View Hint View Answer Discuss in Forum

    Activated effector T cells or CD4+ cells initially contact with the macrophages which possess its receptor and stimulate microbial activity. It also make contact with B cells and stimulate differentiation into plasma cells. On contrary CD8+ cells make contact with B cells and stimulate differentiation into plasma cells. CD4 is a co-receptor that assists the T cell receptor (TCR) in communicating with an antigen-presenting cell. Using its intracellular domain, CD4 amplifies the signal generated by the TCR by recruiting an enzyme, the tyrosine kinase Lck, which is essential for activating many molecular components of the signaling cascade of an activated T cell.

    Correct Option: C

    Activated effector T cells or CD4+ cells initially contact with the macrophages which possess its receptor and stimulate microbial activity. It also make contact with B cells and stimulate differentiation into plasma cells. On contrary CD8+ cells make contact with B cells and stimulate differentiation into plasma cells. CD4 is a co-receptor that assists the T cell receptor (TCR) in communicating with an antigen-presenting cell. Using its intracellular domain, CD4 amplifies the signal generated by the TCR by recruiting an enzyme, the tyrosine kinase Lck, which is essential for activating many molecular components of the signaling cascade of an activated T cell.