Genetics-ⅱ Miscellaneous
- In mismatch correction repair, the parental DNA strand is distinguished from the daughter strand by _____________
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Mismatch repair deals with correcting mismatch of the normal bases using BER or NER enzyme systems. The system assumes that parental strands are methylated and freshly synthesized daughter strands are non methylated.
Correct Option: C
Mismatch repair deals with correcting mismatch of the normal bases using BER or NER enzyme systems. The system assumes that parental strands are methylated and freshly synthesized daughter strands are non methylated.
- A protein is phosphorylated at a serine residue. A phosphomimic mutant of the protein can be generated by substituting that serine with
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To investigate the effect of serine 78 phosphorylation on p21 activity, replacement of serine 78 with aspartic acid is done, creating the phosphomimic p21s78D.
Correct Option: C
To investigate the effect of serine 78 phosphorylation on p21 activity, replacement of serine 78 with aspartic acid is done, creating the phosphomimic p21s78D.
- A truncated polypeptide is synthesized due to a nonsense mutation. Where would you introduce another mutation to obtain a full-length polypeptide?
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Non sense mutations causes premature stop to be introduced that would lead to truncated or incomplete protein synthesis. If the protein synthesis has to be continued, another mutation in t-RNA gene would continue be advised to get full length polypeptide
Correct Option: B
Non sense mutations causes premature stop to be introduced that would lead to truncated or incomplete protein synthesis. If the protein synthesis has to be continued, another mutation in t-RNA gene would continue be advised to get full length polypeptide
- The direction of shell coiling in the snail Limnaea peregra is a classic example of
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The direction of shell coiling in snail is a dassical example for extra
chromosomal inheritance, as in this it is determined by maternal gene effects and not that of the offspring.Correct Option: B
The direction of shell coiling in snail is a dassical example for extra
chromosomal inheritance, as in this it is determined by maternal gene effects and not that of the offspring.
- Which one of the following DNA sequences carries an invert repeat?
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An inverted repeat (or IR) is a sequence of nucleotides followed downstream by its reverse complement. It is a sequence found in identical (but inverted) form, for example, at the opposite ends of a transposon.
Here, the DNA sequence which carries an inverted repeat is:
ATGAGCCCCGAGTA
TACTCGGGGCTCATCorrect Option: B
An inverted repeat (or IR) is a sequence of nucleotides followed downstream by its reverse complement. It is a sequence found in identical (but inverted) form, for example, at the opposite ends of a transposon.
Here, the DNA sequence which carries an inverted repeat is:
ATGAGCCCCGAGTA
TACTCGGGGCTCAT