-
A protein is phosphorylated at a serine residue. A phosphomimic mutant of the protein can be generated by substituting that serine with
-
- glycine
- alanine
- aspartate
- threonine
Correct Option: C
To investigate the effect of serine 78 phosphorylation on p21 activity, replacement of serine 78 with aspartic acid is done, creating the phosphomimic p21s78D.
