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The dissociation constant Kd for ligand binding to the receptor is 10–7 M. The concentration of ligand required for occupying 10% of receptors is
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- 10–6 M
- 10–7 M
- 10–8 M
- 10–9 M
Correct Option: C
Given,
Dissociation constant, Kd = 10–7M
The reaction is: L + R → LR
Thus, Kd for the reaction = [L][R]/[LR]
or [LR]/[LR][R] = 10/100
Therefore, [L] = 1/9 * 10–7M = 10–8M