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Bioenergetics and Metabolism Miscellaneous

Bioenergetics and Metabolism

  1. The equilibrium potential of a biological membrane for Na+ is 55 mV at 37°C. Concentration of Na+ inside the cell is 20 mM. Assuming the membrane is permeable to Na+ only, the Na+ concentration outside the membrane will be _________ mM.
    (Faraday constant: 23062 cal.V–1.mol–1, Gas constant: 1.98 cal.mol–1.K–1)
    1. 147.0 : 170.0
    2. 150.0 180.0
    3. 210.0 : 230.0
    4. 410.0 : 450.0
Correct Option: A

EeqNa' =
RT
In
[Na']n
ZF[Na']

Given EeqNa+ = 55 mV = 55 × 10–3 V
R = 1.98 cal mol–1 K–1
T = 273 + 37 = 310 K
F = 23062 cal V–1 mol–1
[Na+]i = 20 mM.
Z = 1
∴ 55 × 10-3 =
1.98 × 310
In
[Na-]0
1 × 2306220

∴ [Na']0 = 20 × 7.897 = 157.94 mM



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