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The equilibrium potential of a biological membrane for Na+ is 55 mV at 37°C. Concentration of Na+ inside the cell is 20 mM. Assuming the membrane is permeable to Na+ only, the Na+ concentration outside the membrane will be _________ mM.
(Faraday constant: 23062 cal.V–1.mol–1, Gas constant: 1.98 cal.mol–1.K–1)
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- 147.0 : 170.0
- 150.0 180.0
- 210.0 : 230.0
- 410.0 : 450.0
Correct Option: A
EeqNa' = | In | ![]() | ![]() | ||
ZF | [Na'] |
Given EeqNa+ = 55 mV = 55 × 10–3 V
R = 1.98 cal mol–1 K–1
T = 273 + 37 = 310 K
F = 23062 cal V–1 mol–1
[Na+]i = 20 mM.
Z = 1
∴ 55 × 10-3 = | In | ![]() | ![]() | |||
1 × 23062 | 20 |
∴ [Na']0 = 20 × 7.897 = 157.94 mM