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Bioenergetics and Metabolism Miscellaneous

Bioenergetics and Metabolism

  1. The reactions leading to the formation of amino acids from the TCA cycle intermediates are
    1. carboxylation
    2. isomerization
    3. transamination
    4. decarboxylation
Correct Option: C

Transamination refers to the transfer of an amine group from one molecule to another. This reaction is catalyzed by a family of enzymes called transaminases. Actually, the transamination reaction results in the exchange of an amine group on one acid with a ketone group on another acid. It is analogous to a double replacement reaction. The most usual and major keto acid involved with transamination reactions is alpha-ketoglutaric acid, an intermediate in the citric acid cycle. A specific example is the transamination of alanine to make pyruvic acid and glutamic acid.



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