Biotechnology and its Applications
- Read the following four statements (A-D) about certain mistakes in two of them
(A) The first transgenic buffalo, Rosie produced milk which was human alphalactal albumin enriched.
(B) Restriction enzymes are used in isolation of DNA from other macro-molecules.
(C) Downstream processing is one of the steps of R-DNA technology.
(D) Disarmed pathogen vectors are also used in transfer of R-DNA into the host.
Which are the two statements having mistakes?
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Transgenic Rosie is actually cow. Restriction enzymes cut the DNA at specific sites.
Correct Option: D
Transgenic Rosie is actually cow. Restriction enzymes cut the DNA at specific sites.
- Maximum number of existing transgenic animals is of:
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In the world maximum number of existing transgenic animals is mice.
Correct Option: B
In the world maximum number of existing transgenic animals is mice.
- Which body of the Government of India regulates GM research and safety of introducing GM organisms for public services?
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Genetic Engineering Approval Committee is the body of Government of India. It regulates GM research and safety of introducing GM organisms for public service in the country.
Correct Option: B
Genetic Engineering Approval Committee is the body of Government of India. It regulates GM research and safety of introducing GM organisms for public service in the country.
- Genetically engineered bacteria have been successfully used in the commercial production of
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Human insulin has 53 amino acids in two polypeptides (A and B) connected by two S-S (disulphide) linkages. In 1983, American company Eli Lilly prepared two DNA sequences corresponding to A and B insulin chains. When introduced in plamids of E.coli, insulin chains were formed. They were extracted and fused to produce humulin (human insulin).
Correct Option: A
Human insulin has 53 amino acids in two polypeptides (A and B) connected by two S-S (disulphide) linkages. In 1983, American company Eli Lilly prepared two DNA sequences corresponding to A and B insulin chains. When introduced in plamids of E.coli, insulin chains were formed. They were extracted and fused to produce humulin (human insulin).
- What is true for monoclonal antibodies?
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Monoclonal antibodies are identical molecules specific for one type of antigen. These are obtained by injecting the target antigen into a rat or mouse. Sometimes later, the spleen cells producing antibodies are isolated and fused with myeloma cells to produce monoclonal antibodies.
Correct Option: A
Monoclonal antibodies are identical molecules specific for one type of antigen. These are obtained by injecting the target antigen into a rat or mouse. Sometimes later, the spleen cells producing antibodies are isolated and fused with myeloma cells to produce monoclonal antibodies.
