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Which one of the following vectors is used to replace the defective gene in gene therapy?
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- Ti plasmid
- Adenovirus
- Cosmid
- Ri plasmid
Correct Option: B
Adenovirus is non-enveloped dsDNA virus which cause respiratory diseases. Adenovirus is used as a vehicle to administer targeted therapy in the form of recombinant DNA or protein. Specific modifications on fibre proteins are used to target adenovirus to certain cell types, a major effort is made to limit hepatotoxicity and prevent multiple organ failure.
