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  1. Two microbes found to be very useful in genetic engineering are
    1. Vibrio cholerae and a tailed bacteriophage
    2. Diplococcus sp. and Pseudomonas sp.
    3. Crown gall bacterium and Caenorhabditis elegans
    4. Escherichia coli and Agrobacterium tumefaciens
Correct Option: D

Escherichia coli is a bacterium found in human colon. On this bacterium scientists have made extensive genetic experiments to make some vital chemicals like insulin. Another bacterium is Agrobacterium tumefaciens which causes crown gall in plants is extensively used for genetic experiments.



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