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Match the immunoglobulin class in Group I with its properties in Group II
Group I Group II P. IgG 1. Inactivation of kinase G-proteins bronchial mucus Q. IgA 2. Protects against parasites R. IgE 3. Antibody that appears first in serum after exposure to an antigen S. IgM 4. Antibody present in highest concentration in serum
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- P Q R S
4 1 2 3 - P Q R S
3 2 1 4 - P Q R S
4 3 1 2 - P Q R S
1 4 3 2
- P Q R S
Correct Option: A
The bulk of the immunoglobulins is found in the IgG fraction, which also contains most of the antibodies. The IgM molecules are apparently pentamers-aggregates of five of the IgG molecules. Electron microscopy shows their five subunits to be linked to each other by disulfide bonds in the form of a pentagon. The IgA molecules are found principally in milk and in secretions of the intestinal mucosa. Some of them contain, in addition to a dimer of IgG, a “secretory piece” that enables the passage of IgA molecules between tissue and fluid; the structure of the secretory piece is not yet known. The IgM and IgA immunoglobulins and antibodies contain 10 to 15 percent carbohydrate; the carbohydrate content of the IgG molecules is 2 to 3 percent.