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  1. Which of these mice fail to develop a thymus ?
    1. Motheaten mice
    2. Beige mice
    3. Knock out mice
    4. Nude mice
Correct Option: D

A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. The phenotype, or main outward appearance of the mouse is a lack of body hair, which gives it the “nude” nickname. The nude mouse is valuable to research because it can receive many different types of tissue and tumor grafts, as it mounts no rejection response.



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