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Match the activity spectrum of the following antibiotics
P Actinomycin D 1. Antifungal Q Daunorubicin 2. Antituberculosis R Rifamycin 3. Antitumor S Griseofulvin 4. Antiprotosoal
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- P-3 P-3 P-3 P-2
- Q-4 Q-1 Q-1 Q-1
- R-2 R-4 R-2 R-4
- S-1 S-2 S-4 S-3
Correct Option: A
Griseofulvin is an antifungal drug that is administered orally. It is used both in animals and in humans,to treat fungal infections of the skin (known as ringworm) and nails. It is derived from the mold Penicillium griseofulvum. Daunorubicin is chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer. It was initially isolated from Streptomyces peucetius.
The rifamycins are a group of antibiotics that are synthesized either naturally by the bacterium Amycolatopsis mediterranei or artificially. They are a subclass of the larger family Ansamycin. Rifamycins are particularly effective against mycobacteria, and are therefore used to treat tuberculosis, leprosy, and mycobacterium avium complex (MAC) infections.