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When you hold your breath, which of the following gas changes in blood would first lead to the urge to breathe?
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- rising CO2 concentration
- falling CO2 concentration
- rising CO2 and falling O2 concentration
- falling O2 concentration
Correct Option: A
Chemoreceptors in the medulla get stimulated by increase in CO2 concentration in the blood of arteries. Decrease in O2 concentration has no significant effect on chemoreceptors.