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Biochemical Miscellaneous

  1. A bioreactor is scaled up based on equal impeller tip speed. Consider the following parameters for small and large bioreactors: ​​Parameters​Small ​ Large ​​​  bioreactor  bioreactor ​​Impeller speed ​N1 ​N2 ​​Diameter of impeller​ D1 ​D2 ​​Power consumption​ P1​ P2 ​​
    Assuming geometrical similarity and the bioreactors are operated in turbulent regime, what will be P2 / P1?
    1. ​(D1 / D2)2
    2. (D2 / D1)2
    3. (D1 / D2)5
    4. ​(D2 / D1)5
Correct Option: B

Scaled up criteria is equal to impeller tip speed
So​ N1 D1 = ​N2 D2

N2
=
D1
...(i)
N1D2

Now, power equation is given by
P2 ∝ N23 D25
P2
=
N23 D25
=
N2
3
D2
5
P1N13 D15N1D1

=
D1
3
D2
5
N2
=
D1
D2D1N1D2

P2
=
D2
2
P1D1



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