Correct Option: B

Tissue plasminogen activator (t-PA) is a naturally occurring protein that catalyze the conversion of the inactive proenzyme plasminogen into active serine protease plasmin. It is one of the two major endogenous mammalian enzymes with this property and is found in blood and tissues from various organs. Although it exerts a similar enzymatic action, it is structurally different from the other major endogenous enzymes, urokinase. t-PA can be used to treat some people who are having a stroke caused by a blood clot. It plays an important role in cell migration and tissue remodeling.