Direction: A recombinant SV40 virus delivers c-myc cDNA, which has a unique sal I site, into muscle cells. Southern analysis of Sal I digested total genomic DNA of the muscle cell using c-myc cDNA porbe generates a smear.
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Which of the following types of cancer will be observed in such transformed cells ?
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- Adenoma
- Melanoma
- Sarcoma
- Hepatoma
Correct Option: C
Sarcoma is a cancer that arises from transformed cells of mesenchymal origin. Thus, malignant tumors made of cancerous bone, cartilage, fat, muscle, vascular, or hematopoietic tissues are, by definition, considered sarcomas. This is in contrast to a malignant tumor originating from epithelial cells, which are termed carcinoma. Sarcomas are quite rare. Common malignancies, such as breast, colon, and lung cancer, are almost always carcinoma.
