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  1. It is not possible to apply Koch's postulates to
    1. Diptheria
    2. Cholera
    3. Leprosy
    4. Tuberculosis
Correct Option: C

Koch's postulates are not applicable to the bacteria causing leprosy and syphilis. Mycobacterium leprae causing leprosy produces endospores on which Koch’s postulates are not applicable, because Mycobacterium leprae cannot be cultured in vitro.



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