Nuclease-hypersensitive sites in the chromosomes are sites

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Nuclease-hypersensitive sites in the chromosomes are sites that appear to be

1. H2 and H4 histone free
2. H1 and H2 histone free
3. H3 and H4 histone free
4. Nucleosome free

Correct Option: D

Region of eukaryotic chromosome DNA that is specifically vulnerable to nuclease attack perhaps because it is not wrapped in histone as nucleosomes are called the nuclease hypersensitive sites in the chromosomes. Thus they are H₂ and H₄ free, H₁ and H₂ free, H₃ and H₄ histone free.