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Down's syndrome is caused by an extra copy of chromosome number 21. What percentage of offspring produced by an affected mother and a normal father would be affected by this disorder?
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- 25%
- 100%
- 75%
- 50%
Correct Option: D
50% of ova will have (n + 1) chromosome which would, on fertilisation, yield abnormal zygotes (n + 1) + (n) = 2n + 1.