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The most striking example of point mutation is found in a disease called
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- thalassemia
- night blindness
- down's syndrome
- sickle cell anaemia
Correct Option: D
Sickle cell anaemia (in which nucleotide triplet GAG is changed to GUG) affects the
β-globin chain of haemoglobin. Since these changes occur at a particular locus or point of a chromosome where specific gene is located, they are called as point mutation.
