Correct Option: D

Fertilization of ovum is the most likely root cause of when menstruation is not taking place in regularly cycling human female. In order for fertilization to occur, one of these sperm must attach itself to the ovum and penetrate its outer surface. The fertilized ovum will then continue travelling down the fallopian tube, taking several days until it reaches the uterus. When it arrives, it attaches itself to the lining of the uterus and continues to grow. If the ovum is not fertilized it will die and the progesterone and oestrogen hormone levels will drop. Without these hormones the prepared uterus lining breaks up and is released through the vagina. This is known as a ‘period’.