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Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?
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- Chromosomes will be fragmented
- Chromosomes will not segregate
- Recombination of chromosome arms will occur
- Chromosomes will not condense
Correct Option: B
During anaphase, Anaphase Promoting Complex (APC) is a protein necessary for separation of daughter chromosomes. A defective APC will cause the chromosomes fail to segregate during anaphase.