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Select the option which is not correct with respect to enzyme action:
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- Substrate binds with enzyme at its active site.
- Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate.
- A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate.
- Malonate is a competitive inhibitor of succinic dehydrogenase.
Correct Option: B
Inhibitions of succinic dehydrogenase by malonate is an example of competitive inhibition. Thus it is a reversible reaction. On increasing the substrate (succinate) concentration the effect of inhibitor is removed and Vmax remains same.
